| Autor: |
Sascha, Macherey, Max, Schlaak, Fabian, Doerr, Sabine, Grönke, Matthias, Heldwein, Alexander, Quaas, Thomas, Zander, Khosro, Hekmat |
| Jazyk: |
němčina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. 66(1) |
| ISSN: |
1432-1173 |
| Popis: |
Results of previous studies question the benefits of pulmonary surgery in patients with pulmonary metastases from malignant melanoma. A systematic literature search and analysis of articles published since 1 January 2000 was carried out to investigate the advantages of metastasectomy and alternative forms of therapy. Patients reached a median survival time of 17-40 months and 5-year survival rates between 18% and 39.4% after metastasectomy. Intrathoracic recurrence occurred in 30 % of patients but could be successfully treated with re-operations in some cases. Various monoclonal antibodies are currently available and achieve a median survival time of up to 17 months. Pulmonary metastasectomy is the treatment of choice in selected patients; however, in the future the benefits should be revalidated in comparison with pharmaceuticals of the current generation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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