| Autor: |
M, Vahdati, H, Graafland, J M, Emberger |
| Jazyk: |
francouzština |
| Rok vydání: |
1984 |
| Předmět: |
|
| Zdroj: |
Nouvelle revue francaise d'hematologie. 26(3) |
| Popis: |
The karyotypes of 103 cases of B cell chronic lymphocytic leukemia were studied following stimulation or establishment of continuous cell lines using the Epstein-Barr virus. In 52 patients metaphases suitable for cytogenetic analysis were obtained; 30 revealed normal karyotypes and 22 abnormal karyotypes. The most frequently encountered abnormalities were 6 cases of extra chromosome 12, 4 cases of structured aberrations concerning chromosome 14, including 2 t(11;14), 4 translocations concerning chromosome 11, and 3 cases of extra chromosome 3. No relationship appears to exist between the abnormalities observed and the clinical profile or prognosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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