Unusual immunocytochemical and ultrastructural features of synovial fluid cells in multicentric reticulohistiocytosis. A case report

Autor:	S S, Samaan, H R, Schumacher, T, Villanueva, R, Levin, B F, Atkinson
Rok vydání:	1994
Předmět:	Male Microscopy Electron Histiocytosis Non-Langerhans-Cell T-Lymphocytes Biopsy Needle Synovial Fluid Antibodies Monoclonal Humans Middle Aged Immunohistochemistry
Zdroj:	Acta cytologica. 38(4)
ISSN:	0001-5547
Popis:	We present the first report in which cells in synovial fluid from a patient with multicentric reticulohistiocytosis (MRH) were studied by immunocytochemistry for correlation with routine light and electron microscopy. MRH cells stained predominantly for lymphocyte-related surface antigens and not for the monocyte marker LEU M3 (CD14). These findings suggest a lymphocytic origin of MRH cells and not a histiocytic origin, as previously suggested. In addition, large numbers of membrane-bound, electron-dense, secretory-type granules were found ultrastructurally in the cytoplasm of these cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::51fb0189825b01a2d7614296e65ac6ae https://pubmed.ncbi.nlm.nih.gov/8042427 Zobrazit plný text záznamu