[Preparation of monoclonal antibodies to the Fc-fragment of human IgG and the use of their based immunoenzyme conjugates]

Autor:	I V, Nikolaenko, A Iu, Galkin, G E, Raevskaia, T V, Kas'ianenko, M I, Nereshchenko, E S, Donskaia, N Ia, Spivak
Rok vydání:	2006
Předmět:	Hybridomas Immunoglobulin G Antibodies Monoclonal Humans Enzyme-Linked Immunosorbent Assay Reagent Kits Diagnostic Sensitivity and Specificity Horseradish Peroxidase Immunoglobulin Fc Fragments
Zdroj:	Klinicheskaia laboratornaia diagnostika. (11)
ISSN:	0869-2084
Popis:	An original kit containing 17 clones of hybridomas, the producers of monoclonal antibodies (MCAb) against the Fc-fragments of human IgG, has been obtained. The possibility of using horseradish peroxidase conjugates of obtained MCAb as a part of ELISA test systems (Diaproph-Med, Ukraine) was comparatively studied. The application of peroxidase conjugates of two monoclonal antibodies (156C10 and 153H11) as part of five diagnostic kits was shown to provide a high specificity and a high sensitivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::51eec7356b6e4264779f08dafccc2d8b https://pubmed.ncbi.nlm.nih.gov/16404968 Zobrazit plný text záznamu