[Activity of lysosomal hydrolases and renewal of proteins in the rat liver, spleen, and thymus during antigenic stimulation and protein deficiency]

Autor:	A V, Vasil'ev, L S, Konovalova, K D, Pletsityĭ, L G, Ponomareva, V A, Tutel'ian
Rok vydání:	1989
Předmět:	Male Hydrolases Proteins Rats Inbred Strains Thymus Gland Cathepsin C Cathepsin B Rats Liver Protein Deficiency Animals Immunization Antigens Dipeptidyl-Peptidases and Tripeptidyl-Peptidases Lysosomes Spleen Half-Life Subcellular Fractions
Zdroj:	Voprosy meditsinskoi khimii. 35(1)
ISSN:	0042-8809
Popis:	Activity of cathepsins B and C was increased 1.8-2-fold in spleen simultaneously with a decrease 3.8-fold in the rate of protein renewal in the tissue lysosomal fraction within 4 days after antigen stimulation of rats, maintained within 45 days on a diet containing 5% of protein. Activation of these thiol-dependent proteinases appears to occur in response to development of immunodepressive conditions and may be related to alterations in the rate of their biosynthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::51d851c9420625ad250df7938b91d973 https://pubmed.ncbi.nlm.nih.gov/2741402 Zobrazit plný text záznamu