Microbiological analysis of infected root canals from symptomatic and asymptomatic teeth with periapical periodontitis and the antimicrobial susceptibility of some isolated anaerobic bacteria
| Autor: | R C, Jacinto, B P F A, Gomes, C C R, Ferraz, A A, Zaia, F J Souza, Filho |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Chi-Square Distribution Gram-Negative Anaerobic Bacteria Adolescent Amoxicillin Pain Microbial Sensitivity Tests Penicillins Middle Aged Amoxicillin-Potassium Clavulanate Combination Anti-Bacterial Agents Bacteria Anaerobic Edema Humans Drug Therapy Combination Female Cefaclor Dental Pulp Cavity Gram-Negative Bacterial Infections Periapical Periodontitis |
| Zdroj: | Oral microbiology and immunology. 18(5) |
| ISSN: | 0902-0055 |
| Popis: | The purpose of the present study was to investigate the correlation between the composition of the bacterial flora isolated from infected root canals of teeth with apical periodontitis with the presence of clinical signs and symptoms, and to test the antibiotic susceptibility of five anaerobic bacteria mostly commonly found in the root canals of symptomatic teeth against various substances using the E-test. Microbial samples were taken from 48 root canals, 29 symptomatic and 19 asymptomatic, using adequate techniques. A total of 218 cultivable isolates were recovered from 48 different microbial species and 19 different genera. Root canals from symptomatic teeth harbored more obligate anaerobes and a bigger number of bacterial species than the asymptomatic teeth. More than 70% of the bacterial isolates were strict anaerobes. Statistical analysis used a Pearson Chi-squared test or a one-sided Fisher's Exact test as appropriate. Suggested relationships were found between specific microorganisms, especially gram-negative anaerobes, and the presence of spontaneous or previous pain, tenderness to percussion, pain on palpation and swelling amoxicillin, amoxicillin + clavulanate and cephaclor were effective against all the strains tested. The lowest susceptibility rate was presented by Prevotella intermedia/nigrescens against Penicillin G. Our results suggested that specific bacteria are associated with endodontic symptoms of infected teeth with periapical periodontitis and the majority of the anaerobic bacterial species tested were susceptible to all antibiotics studied. |
| Databáze: | OpenAIRE |
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