Translation of the prophage lambda cl transcript
Autor: | C S, Shean, M E, Gottesman |
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Rok vydání: | 1992 |
Předmět: |
Ribosomal Proteins
Base Sequence Genes Viral Transcription Genetic Blotting Western Molecular Sequence Data DNA Single-Stranded Regulatory Sequences Nucleic Acid beta-Galactosidase Bacteriophage lambda DNA-Binding Proteins Repressor Proteins Viral Proteins Protein Biosynthesis RNA Ribosomal 16S Mutation Escherichia coli RNA Viral Viral Regulatory and Accessory Proteins Codon Plasmids |
Zdroj: | Cell. 70(3) |
ISSN: | 0092-8674 |
Popis: | Mutations in rpsB that reduce the levels of the ribosomal protein S2 enhance the translation of cl in lambda lysogens. Two features of the cl transcript are required for enhanced translation: the absence of a leader and the presence of a downstream box, a sequence within the cl coding region that is complementary to the 16S rRNA. 30S ribosomal subunits deficient in S2 form ternary complexes with the cl transcript more efficiently than wild-type subunits. The absence of S2 may change the structure of the 16S rRNA, improving contacts with the cl downstream box. |
Databáze: | OpenAIRE |
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