| Autor: |
S, Garbisa, M, Onisto, L, Mazzanti, A L, Tranquilli, A, Pugnaloni, G, Biagini, N, Cester, C, Romanini |
| Rok vydání: |
1993 |
| Předmět: |
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| Zdroj: |
Clinical and experimental obstetricsgynecology. 20(4) |
| ISSN: |
0390-6663 |
| Popis: |
The objective of this study was to determine whether cultured trophoblast cells shared the same morphological and biological properties observed in trophoblast, in vivo.Trophoblast cells from human term placenta were cultured, morphologically, biochemically and immunochemically monitored for as long as 30 days.Single cells progressively aggregated and fused into a syncytio, the Ca2+ and the Ca(2+)-ATPase activity drooped, and the 72 kDa collagenase (MMP-2) was consistently expressed.Term placenta trophoblast cultures can be viewed and used as a model system mimicking morphological and biochemical events of placenta biology and differentiation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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