| Autor: |
R, Genthon, F, Gray, J, Salama, C, Duyckaerts, C, Belin, J M, Brucher, H, Baron, P, Delaporte |
| Jazyk: |
francouzština |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
Revue neurologique. 148(5) |
| ISSN: |
0035-3787 |
| Popis: |
Gerstmann-Sträussler-Scheinker's disease is a familial spongiform encephalopathy whose pathological hallmark is the existence--especially in the cerebellum--of numerous amyloid plaques. We report here the third clinicopathological case in a French family. Brain tissue from one of its members--initially described as familial Creutzfeldt-Jakob's disease--has been reported as successfully inoculated to monkeys. We present the currently accumulating data favouring the hypothesis of a common etiology for familial Creutzfeldt-Jakob's disease and Gerstmann-Sträussler-Scheinker's disease. The familial characteristics, resulting in different durations of incubation and evolution, could lead to different clinical and histological expressions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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