[Intraneuronal information processing. An increase in sodium and decrease in potassium permeability after injection of cyclic nucleotide and mechanical stimulation of the neuron]

Autor:	E A, Liberman, S V, Minina, O L, Miakotina, N E, Shklovskiĭ-Kordi
Rok vydání:	1985
Předmět:	Neurons Cell Membrane Permeability Sodium Cyclic AMP Potassium Pressure Action Potentials Animals In Vitro Techniques Iontophoresis Cyclic GMP Ion Channels
Zdroj:	Biofizika. 30(4)
ISSN:	0006-3029
Popis:	In voltage clamp experiments the ionic permeability mechanism of the neuron soma evoked by the injection of cyclic nucleotides can be estimated only by studying the reversal potential. The value of this potential allows to conclude that permeability is mainly increased by opening potential independent sodium channels. A delay of ionic current evoked by cyclic nucleotides is tenfold less than the time of cAMP diffusion to the membrane. This leads to a hypothesis about the cyclic nucleotide dependent mechanical opening of sodium channels.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4fede89c979515d395e95f52eb1fb8d1 https://pubmed.ncbi.nlm.nih.gov/2413903 Zobrazit plný text záznamu