[Effect of Acupuncture on Expression of Receptor Tyrosine Kinase c-kit in Interstitial Cells of Cajal, Carbon Monoxide and Heme Oxygenase in Colon Tissue After Colonic Anastomosis in Rats]

Autor: Jing-Jing, Deng, Qing, Yuan, Man-Xia, Wang, Yi-Zong, Yang
Rok vydání: 2017
Předmět:
Zdroj: Zhen ci yan jiu = Acupuncture research. 42(4)
ISSN: 1000-0607
Popis: To observe the effect of acupuncture on expression of receptor tyrosine kinase (RTK) c-kit in interstitial cells of Cajal (ICCs), carbon monoxide (CO) and heme oxygenase (HO) in colon tissue after colonic anastomosis, so as to explore the mechanism of acupuncture in improving gastrointestinal motility.SD rats were randomly devided into control group, model group and acupuncture group. The model was established using colonic anastomosis. Each group was further devided into 3, 5, and 10 d (time-point) subgroups (Compared to the control group, the intestinal propulsive rate and the expression level of c-kit in ICCs were decreased in the model group(Acupuncture can improve postoperative gastrointestinal motility by declining CO content and HO-1 and HO-2 activity in colon tissue, and promoting ICCs restoration.
Databáze: OpenAIRE