[Antioxidative effects of isoflavon genisteine-8-C-glycoside in vitro and in vivo]

Autor: L B, Zavodnik, A P, Shkodich, M, Wielanek, A I, Egorov, I B, Zavodnik, Iu V, Popov, V A, Ovchinnikov, N A, Laman, V U, Buko
Rok vydání: 2006
Předmět:
Zdroj: Eksperimental'naia i klinicheskaia farmakologiia. 69(1)
ISSN: 0869-2092
Popis: Bioflavonoids (polyhydroxyphenols) are ubiquitous components of plants, fruits and vegetables; these compounds are efficient scavengers of free oxygen radicals and peroxides. The aim of this study was to investigate the antioxidative effects of genistein-8-C-glycoside (G8CG) isolated from the flowers of Lipinus luteus L. G8CG dose-dependently inhibited membrane lipid peroxidation and prevented GSH oxidation in human red blood cells and rat liver homogenates under tert-butylhydroperoxide-induced oxidative stress and single whole-body gamma-irradiation (1 Gy) of rats.
Databáze: OpenAIRE