[The use of donor blood plasma with a high titer of natural antiendotoxin antibodies, irradiated by ultraviolet light, in the combined detoxification therapy of peritonitis]

Autor: A V, Apollonin, A A, Rudik, E I, Kropacheva, V G, Likhoded
Rok vydání: 1994
Předmět:
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii. (2)
ISSN: 0372-9311
Popis: The ultraviolet (UV) irradiation of donor blood plasma with an elevated level of natural antibodies to Re-glycolipid with doses ranging from 100 to 200 J/m2 has been found to lead to a statistically significant rise in its protective activity. The use of such plasma in clinical practice has made it possible to decrease the frequency of lethal outcomes from 24.3% to 16.5% (p0.01), the occurrence of secondary infectious complications from 62% to 44.4% (p0.01) and the duration of patients' stay in a hospital by 6-8 days. These data make it possible to regard the use of UV-irradiated plasma with an elevated level of Re-antibodies as an effective method of the immunotherapy of septic complications caused by gram-negative bacteria.
Databáze: OpenAIRE