| Autor: |
F M, Yorulmaz, E, Kuralay, H, Tatar, H, Süer, O Y, Oztürk |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Cardiovascular surgery (London, England). 1(4) |
| ISSN: |
0967-2109 |
| Popis: |
In an attempt to resolve the controversy concerning use of beta-adrenoceptor blockade in patients undergoing coronary artery revascularization, 40 consecutive patients with ischaemic heart disease receiving chronic beta-adrenergic blocking therapy (study group) were entered into a randomized trial and were compared with 40 patients receiving no beta-blocking therapy (control group). The postoperative requirement for positive inotropic agents between the two groups was compared. The clinical and operative characteristics of the two groups were similar. After surgery, 2% of patients in the study group required positive inotropic agents compared with 18% of those in the control group (P0.05). It is concluded that this difference resulted from an increase in density of beta 1-adrenergic receptors induced by beta-adrenergic blockade, and an increase in the level of catecholamines in the early postoperative period. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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