[A rare case of a sclerodermoid chronic graft versus host disease. Successful treatment with extracorporeal photopheresis (ECP)]

Autor:	A G, Jung, H P, Bertsch, M P, Schoen, U, Lippert
Jazyk:	němčina
Rok vydání:	2010
Předmět:	Adult Anemia Refractory with Excess of Blasts Biopsy Graft vs Host Disease Lichen Sclerosus et Atrophicus Photopheresis Chronic Disease Scleroderma Diffuse Humans Female Atrophy Follow-Up Studies Skin Stem Cell Transplantation
Zdroj:	Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. 61(6)
ISSN:	1432-1173
Popis:	A 31-year-old woman presented with progressive deep linear induration on her lower abdomen, forearms and thighs. These symptoms developed three years after allogenic stem cell transplantation. Furthermore, the patient showed multiple hypopigmented lichenoid papules on the extensor surfaces of the forearms consistent with lichen sclerosus. Histological analysis of a biopsy specimen from her left thigh showed dermal sclerosis extending into the fascia, thus establishing the diagnosis of a rare combination of superficial and deep sclerodermoid chronic graft-versus-host disease. After 7 cycles of extracorporeal photopheresis, a marked resolution of the indurations and a reduction of the modified Rodnan skin score from 12 to 7 were noted.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4eb3f9dc6888d1d80b1e23f9f2df355e https://pubmed.ncbi.nlm.nih.gov/20309512 Zobrazit plný text záznamu Full text from SpringerLink