| Autor: |
A, Allegretti, R, Lionetto, S, Saccomanno, M, Paganuzzi, M, Onetto, C, Martinoli, G, Rollandi, M, Marugo, L, Fazzuoli, V, Pugliese |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Oncology. 50(2) |
| ISSN: |
0030-2414 |
| Popis: |
In this phase II study, we treated 7 patients, all males, with stage III or IV pancreatic cancer with goserelin (an LH-RH analogue). Goserelin was administered at a dose of 3.6 mg every 4 weeks. The tumour response was assessed by measuring lesions with US- or CT-scan studies, according to WHO criteria. No response was observed. The median survival was 8 months in locally unresectable tumours and 4 months in advanced disease. The accrual was actually stopped at 7 cases because there were no responses in either of our series or in those published during our study. The authors conclude that the treatment with LH-RH analogue alone cannot be recommended for further studies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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