[Effect of levamisole on the activity of the blood T-lymphocytes and of factors they produce in patients with laryngeal cancer]

Autor: L I, Volosevich, E V, Lukach, L D, Krivokhatskaia
Rok vydání: 1988
Předmět:
Zdroj: Eksperimental'naia onkologiia. 10(3)
ISSN: 0204-3564
Popis: The functional activity of T-lymphocytes was studied in 20 donors and in 59 patients with laryngeal tumours, stages II to IV. A considerable decrease in the activity of T-lymphocytes was observed in patients with laryngeal cancer, stages III and IV. Levamisole increased the functional activity of T-lymphocytes in vitro. It was found that spontaneous rosette-formation, PHA-induced lymphocyte proliferation and gamma-interferon production increased while the activity of suppressor T-lymphocytes induced by concanavalin A decreased.
Databáze: OpenAIRE