Antimicrobial activity of chloramphenicol in solid dispersion systems

Autor:	A A, Kassem, S A, Zaki, N M, Mursi, S A, Tayel
Rok vydání:	1979
Předmět:	Dosage Forms Chloramphenicol Escherichia coli Hydrogen-Ion Concentration
Zdroj:	Die Pharmazie. 34(1)
ISSN:	0031-7144
Popis:	The effect of solid dispersion techniques on the antimicrobial activity of chloramphenicol has been studied and it was proven that the antimicrobial activity of chloramphenicol is not affected when the drug is present as a coprecipitate with carbowaxes (4.000, 6.000, 12.000), and PVP 11.000 and 40.000) also in fusion systems with these polymers. In contrast, the antimicrobial activity of the drug is enhanced when it is present in the from of a solid dispersion system.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4e22b8fce8e33dc8d007891eff17d343 https://pubmed.ncbi.nlm.nih.gov/34838 Zobrazit plný text záznamu