[A Case of Unresectable Pancreas Cancer with 32 Months Survival after Chemotherapy]

Autor: Hidetoshi, Amagasa, Akira, Fukuda, Azusa, Yamada, Ryuta, Kakuta, Daisuke, Kajiyama, Machiko, Kawaguchi, Go, Shibuya, Shinsuke, Maeda, Kazuo, Motoyama, Hideaki, Ganno, Kenichirou, Imai, Katsunori, Ami, Satoshi, Iida, Masayuki, Andou
Rok vydání: 2019
Předmět:
Zdroj: Gan to kagaku ryoho. Cancerchemotherapy. 45(13)
ISSN: 0385-0684
Popis: We report a case of unresectable pancreas cancer. A 70-year-old woman presented with worsening diabetes and serum CA19-9 elevation. A tumor with portal vein and supra-mesenteric vein invasion was observed by computed tomography. She was diagnosed with unresectable pancreas head cancer that was locally advanced. Chemotherapy was administered with gemcitabine and nab-paclitaxel for 19 courses, followed by gemcitabine alone for 4 courses. After the addition of 6 courses of chemotherapy, a 60%dose of chemotherapy was administered for 13 courses due to severe neutropenia. The patient died 32 months after the first visit. The 60% dose of gemcitabine and nab-paclitaxel also inhibited tumor growth. These findings suggest the effective and safe long-term use of gemcitabine and nab-paclitaxel.
Databáze: OpenAIRE