| Autor: |
Nahideh, Asadi, Nasim, Annabi, Ebrahim, Mostafavi, Maryam, Anzabi, Rovshan, Khalilov, Siamak, Saghfi, Masoud, Mehrizadeh, Abolfazl, Akbarzadeh |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Artificial cells, nanomedicine, and biotechnology. 46(sup1) |
| ISSN: |
2169-141X |
| Popis: |
Magnetic nanoparticles have properties that cause to apply them in cancer therapy and vehicles for the delivery of drugs such as 5FU, especially when they are modified with biocompatible copolymers. The aim of this study is to modify superparamagnetic iron oxide nanoparticles (SPIONPs) with PCL-PEG-PCL copolymers and then utilization of these nanoparticles for encapsulation of anticancer drug 5FU. The ring-opening polymerization (ROP) was used for the synthesis of PCL-PEG-PCL copolymer by ε-caprolactone (PCL) and polyethylene glycol (PEG2000). We used the double emulsion method (water/oil/water) to prepare 5FU-encapsulated Fe |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
