Successful pregnancy complicated by persistent pneumothorax in a patient with lymphangioleiomyomatosis (LAM) on sirolimus

Autor: M, Faehling, S, Frohnmayer, M, Leschke, B, Trinajstic-Schulz, J, Weber, F, Liewald
Rok vydání: 2011
Předmět:
Zdroj: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. 28(2)
ISSN: 1124-0490
Popis: We report a successful pregnancy in a patient with longstanding LAM on treatment with sirolimus. During temporary discontinuation fo sirolimus in early pregnancy, lung function declined but recovered after resumption of sirolimus. Pregnancy was complicated by a persistent pneumothorax which was treated surgically postnatally. The child has had a normal development despite exposure to low dose sirolimus intermittently during early embryonal and mid-fetal life.
Databáze: OpenAIRE