Severe multicentric reticulohistiocytosis: disease stabilization achieved with methotrexate and hydroxychloroquine

Autor: J M, Cash, J, Tyree, M, Recht
Rok vydání: 1998
Předmět:
Zdroj: The Journal of rheumatology. 24(11)
ISSN: 0315-162X
Popis: Multicentric reticulohistiocytosis is a rare systemic disease that typically manifests as erosive polyarthritis. The particularly aggressive nature of multicentric reticulohistiocytosis has led many to recommend treatment with high dose corticosteroids, alkylating agents, or both. We describe a 56-year-old woman with erosive polyarthritis successfully treated exclusively for 30 months with hydroxychloroquine and methotrexate. This regimen may have the potential to provide longterm disease control with reduced risk of serious drug related toxicity.
Databáze: OpenAIRE