Cholesterol Accumulation in CD11c

Autor: Ayaka, Ito, Cynthia, Hong, Kazuhiro, Oka, Jon V, Salazar, Cody, Diehl, Joseph L, Witztum, Mercedes, Diaz, Antonio, Castrillo, Steven J, Bensinger, Lawrence, Chan, Peter, Tontonoz
Rok vydání: 2016
Předmět:
Zdroj: Immunity. 45(6)
ISSN: 1097-4180
Popis: Liver X receptors (LXRs) are regulators of cholesterol metabolism that also modulate immune responses. Inactivation of LXR α and β in mice leads to autoimmunity; however, how the regulation of cholesterol metabolism contributes to autoimmunity is unclear. Here we found that cholesterol loading of CD11c
Databáze: OpenAIRE