Autor: |
Ayaka, Ito, Cynthia, Hong, Kazuhiro, Oka, Jon V, Salazar, Cody, Diehl, Joseph L, Witztum, Mercedes, Diaz, Antonio, Castrillo, Steven J, Bensinger, Lawrence, Chan, Peter, Tontonoz |
Rok vydání: |
2016 |
Předmět: |
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Zdroj: |
Immunity. 45(6) |
ISSN: |
1097-4180 |
Popis: |
Liver X receptors (LXRs) are regulators of cholesterol metabolism that also modulate immune responses. Inactivation of LXR α and β in mice leads to autoimmunity; however, how the regulation of cholesterol metabolism contributes to autoimmunity is unclear. Here we found that cholesterol loading of CD11c |
Databáze: |
OpenAIRE |
Externí odkaz: |
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