Autor: |
Somayeh, Soleymanzadeh Moghadam, Nazanin, Mohammad, Maryam, Ghooshchian, Sara, FathiZadeh, Zohreh, Khodaii, Mahmood, Faramarzi, Zeinab, Fagheei Aghmiyuni, Masoud, Roudbari, Abdolreza, Pazouki, Tahereh, Mousavi Shabestari |
Rok vydání: |
2019 |
Předmět: |
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Zdroj: |
Medical Journal of the Islamic Republic of Iran |
ISSN: |
1016-1430 |
Popis: |
Background: Infection of burn wounds is one of the most important problems in the world. Lactobacillus plantarum is known for burn wound healing because of the immunomodulatory and anti-microbial roles. This study was performed to compare the effects of L. plantarum and imipenem – alone and in combination – on infected burn wound healing. Methods: Burn wounds were experimentally induced on 50 rats in three test groups (germ and supernatant of L. plantarum ) and two control groups (n=10 each) and were inoculated with Pseudomonas aeruginosa. During a 14-day period, wounds in all groups were daily treated topically. The data were analyzed using one-way analysis of variance followed by Tukey–Kramer and LSD. A p-value of < 0.05 was considered as statistically significant. Results: The mean size of the wound on day 14 after the treatment in the probiotic group was significantly lower than the control and the supernatant treated groups (p |
Databáze: |
OpenAIRE |
Externí odkaz: |
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