Estimation of the copper-iron correlation in the liver under experimental conditions. A microscopic and microchemical study

Autor:	I, Cuida, D, Onicescu, N, Ionescu
Rok vydání:	1980
Předmět:	Microscopy Electron Hepatolenticular Degeneration Liver Iron Animals Copper Electron Probe Microanalysis Rats
Zdroj:	Morphologie et embryologie. 26(3)
ISSN:	0377-5038
Popis:	Liver obtained from copper-intoxicated rats was studied by electron microscopy and electron probe microanalysis. Large ultrastructural disorders in liver cells appeared at the level of lysosomes and mitochondria. Diffuse and aggregate copper granules were observed in the entire cell, but mainly in pericentrolobular and periportal zones. Probe analysis revealed an increased copper deposit, particularly during the chronic copper intoxication, and a very high concentration of iron gradually accumulated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4d3840777f55a02b9a6135c127bf8351 https://pubmed.ncbi.nlm.nih.gov/6453285 Zobrazit plný text záznamu