BRAF

Autor: Yo-Ting, Tsai, Aparna, Lakshmanan, Amy, Lehman, Bonnie K, Harrington, Fabienne McClanahan, Lucas, Minh, Tran, Ellen J, Sass, Meixiao, Long, Alan D, Flechtner, Florinda, Jaynes, Krista, La Perle, Vincenzo, Coppola, Gerard, Lozanski, Natarajan, Muthusamy, John C, Byrd, Michael R, Grever, David M, Lucas
Rok vydání: 2017
Předmět:
Zdroj: Blood advances. 1(24)
ISSN: 2473-9529
Popis: Mutated mitogen-activated protein kinase (MAPK) pathway components promote tumor survival, proliferation, and immune evasion in solid tumors. MAPK mutations occur in hematologic cancers as well, but their role is less clear and few models are available to study this. We developed an in vivo model of disseminated BRAF
Databáze: OpenAIRE