IgG subclasses specific to Staphylococcus epidermidis and Propionibacterium acnes in patients with acne vulgaris

Autor:	H R, Ashbee, S R, Muir, W J, Cunliffe, E, Ingham
Rok vydání:	1997
Předmět:	Adult Male Adolescent Antibody Specificity Immunoglobulin G Acne Vulgaris Staphylococcus epidermidis Humans Female Propionibacterium acnes Antibodies Bacterial
Zdroj:	The British journal of dermatology. 136(5)
ISSN:	0007-0963
Popis:	IgG subclasses specific to Staphylococcus epidermidis and Propionibacterium acnes were determined in sera from patients with mild, moderate or severe acne and from a control group. Titres specific to S. epidermidis were all within the same range and did not differ between groups. The titres of IgG subclasses to specific to P. acnes did vary between groups. IgG1 and IgG3 were significantly higher in severe acne patients compared with moderate acne patients, while IgG2 was significantly higher in moderate and severe patients compared with controls. Titres of IgG4 did not differ between groups. The pattern of titres observed suggests that, while the antibody response to S. epidermidis is relatively harmless, antibodies to P. acnes may be involved in the pathogenesis of acne vulgaris.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4d26c158478e1e757cef62fcb47b626c https://pubmed.ncbi.nlm.nih.gov/9205507 Zobrazit plný text záznamu Plný text