[Effect of immunomodulators on resistance to gas gangrene. The enhanced resistance of white mice to perfringens toxin type A as affected by prodigiozan]

Autor:	R E, Konikova, A V, Stepanov, L P, Sviridov
Rok vydání:	1986
Předmět:	Time Factors Clostridium perfringens Bacterial Toxins Calcium-Binding Proteins Polysaccharides Bacterial Drug Evaluation Preclinical Drug Resistance Immunity Innate Mice Prodigiozan Adjuvants Immunologic Type C Phospholipases Animals Gas Gangrene
Zdroj:	Zhurnal mikrobiologii, epidemiologii i immunobiologii. (2)
ISSN:	0372-9311
Popis:	Experiments on 575 noninbred white mice have revealed that the nonspecific resistance of the animals to type A C. perfringens toxin can be enhanced by the administration of Prodigiosan, a commercial immunostimulating agent. Prodigiosan, introduced in 3-4 injections (the last one made 24 hours before intoxication) has been found to enhance the resistance of the animals to the subcutaneous injection of type A C. perfringens toxin by 40-60% and to its intraperitoneal injection by 60-97%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4d23e869c1f43ac760d5f34bfb59a67d https://pubmed.ncbi.nlm.nih.gov/2870596 Zobrazit plný text záznamu