[Influenza virus in pediatrics. A reason for hospitalization]
| Autor: | Marta, Cruz-Cañete, David, Moreno-Pérez, Antonio, Jurado-Ortiz, Francisco Jesús, García-Martín, Juan, López-Siles, Laura, Olalla-Martín |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Adolescent Influenza A Virus H3N2 Subtype Vaccination Infant Comorbidity Hospitals Maternity Hospitals Pediatric Polymerase Chain Reaction Hospitalization Early Diagnosis Influenza A Virus H1N1 Subtype Influenza Vaccines Risk Factors Spain Child Preschool Nasopharynx Influenza Human Humans RNA Viral Female Prospective Studies Viremia Child |
| Zdroj: | Enfermedades infecciosas y microbiologia clinica. 25(3) |
| ISSN: | 0213-005X |
| Popis: | Influenza infection in infants and children has been classically underestimated due to its non-specific symptoms, which sometimes overlap those of other respiratory viruses. Infants under 24 months are a risk group and school-aged children are a major source of influenza infection. The aim of this study was to describe the clinical and epidemiological characteristics of children hospitalized for flu, including co-infections and the differences as compared to other respiratory viruses. The effectiveness of a test for rapid diagnosis of this condition was assessed.Prospective, descriptive study in children5 years of age hospitalized from 1 December 2003 to 28 February 2004 with respiratory processes or fever of unknown origin. Polymerase chain reaction (PCR) testing for influenza A (IA) and B, respiratory syncytial virus A (RSV-A) and B, and parainfluenza 1, 2 and 3 was performed in nasopharyngeal aspirate, as well as a test for rapid diagnosis of influenza.A total of 203 samples were included. PCR was positive for influenza in 11.3% (23/203); IA in 21 cases (20 H3N2, 1 H1N1). Co-infections were frequent (10/23), mainly IA with RSV-A. The rapid diagnostic test had a sensitivity of 45.5%. Median age of patients with flu was 4.87 months (5 days-3.5 years); 69.5% were24 months. Gastrointestinal symptoms were associated with fever and respiratory symptoms more often than in other viral infections (P0.05). Only 2.9% of patients with a recommendation for flu vaccination had received the vaccination.Flu is a major cause of hospitalization in infants and children, particularly those aged24 months. Early diagnosis of this condition may avoid unnecessary use of additional tests and antibiotics. Vaccination coverage is low; vaccination between 6 and 24 months seems advisable. |
| Databáze: | OpenAIRE |
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