[Study of the Drosophila melanogaster trf2 gene and its protein product]

Autor: D V, Kopytova, Iu V, nikolenko, L A, Lebedeva, E N, Nabirochkina, Iu V, Shidlovskiĭ, S G, Georgieva, A N, Krasnov
Rok vydání: 2008
Předmět:
Zdroj: Genetika. 44(2)
ISSN: 0016-6758
Popis: The Drosophila melanogaster TRF2 protein regulates transcription of several genes. The trf2 gene structure was studied. The gene proved to code for two protein isoforms, a known 75-kDa isoform and a newly identified 175-kDa isoform. The new isoform combines the known isoform sequence with an extended N end containing a coiled-coil motif. The long TRF2 isoform was found to act as a component of a multiprotein complex, including ISWI ATPase as well.
Databáze: OpenAIRE