| Autor: |
P H, Pan, Q L, Chen, E S, Wu |
| Rok vydání: |
2003 |
| Předmět: |
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| Zdroj: |
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University. 26(4) |
| ISSN: |
1000-5625 |
| Popis: |
To investigate the role of alveolar macrophages in airway remodeling in asthma.Sixteen Wistar rats were divided into two groups: control group and asthmatic group. The expressions of platelet-derived growth factor-b (PDGF-b) and transforming growth factor-beta. (TGF-beta 1) in the alveolar macrophages of allergic rats were detected by immunohistochemistry and in situ hybridization.The expression of TGF-beta 1 in alveolar macrophages in allergic group was increased in both protein level (P0.05) and TGF-beta 1 mRNA(P0.01); but the expression of PDGF-b had no difference between the two groups.The alveolar macrophages may involve in the airway remodeling of asthma. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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