[The age-dependent incidence of Down's syndrome and the free-radical theory]

Autor:	S B, Arbuzova
Rok vydání:	1996
Předmět:	Adult Aging Adolescent Free Radicals Pregnancy Incidence Luminescent Measurements Humans Female Down Syndrome Middle Aged Ukraine Maternal Age
Zdroj:	TSitologiia i genetika. 30(5)
ISSN:	0564-3783
Popis:	Age-dependent distribution of Down syndrome frequency in the light of free-radical theory of aging was carried out in this work. The frequency of Down syndrome had been analysed during the period of 1990-1995. The investigation of radical process intensity was performed in the group of women of child-bearing age by the chemoluminescence method. It has been demonstrated that the age of a woman is one of the main reasons both of Down syndrome frequency increase and free radical accumulation. The obtained analogy between age-dependent distribution of Down syndrome frequency and age-dependent accumulation of free radicals is one more argument for the role of free radicals in the pathogenesis of Down syndrome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4c3b30d18f26fc8dce173687073392e7 https://pubmed.ncbi.nlm.nih.gov/9026987 Zobrazit plný text záznamu