Primary malignant melanoma of the bladder - case report and literature overview

Autor: Gheorghe Adrian, Bumbu, Mihail Claudius, Berechet, Ovidiu Laurean, Pop, Karim, Nacer, Gheorghe, Bumbu, Octavian Adrian, Maghiar, Ovidiu Gabriel, Bratu, Mihai Lucian, Ştefănescu, Carmen, Pantiş, Bogdan Andrei, Bumbu
Rok vydání: 2019
Předmět:
Zdroj: Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. 60(1)
ISSN: 2066-8279
Popis: Malignant melanoma is one of the common skin cancers but as a primary cancer localized in urinary bladder is a very rare clinical entity, 0.2% of all melanomas. We report the very rare case of primary malignant melanoma of the bladder in an 80-year-old man. According with our knowledge is the first case of primary malignant melanoma reported in Romania. Only a few percent of malignant melanoma have origin outside the skin. Less than 30 cases of primary bladder melanoma have been reported in the literature. The most common metastasis in urinary bladder comes from breast carcinoma and skin melanoma The tissue examination presents the same futures does not matter if is a primary or secondary malignant melanoma. The ancillary tests like immunohistochemistry help us to do an accurate diagnostic but to discriminate primary vs. metastatic tumor remain an important issue. Usually, the bladder melanoma has an aggressive lethal behavior. Histopathological examination, immunohistochemistry, clinical history, and endoscopic evaluation can provide certain diagnostic features.
Databáze: OpenAIRE