Rationale and Preclinical Evaluation of a Multimodal Topical Body Skincare Product for Toning and Tightening

Autor: Kevin, Smith, Patrick, Nido, Prithwiraj, Maitra, Tsing, Cheng, Kuniko, Kadoya
Rok vydání: 2021
Předmět:
Zdroj: Journal of drugs in dermatology : JDD. 20(10)
ISSN: 1545-9616
Popis: A novel tightening and toning cream (TTC) was designed to improve body skin quality at multiple levels by engaging several key pathways that contribute to skin function, strength, and integrity. Evaluation of gene expression in both human in vitro 3D skin and ex vivo skin treated with TTC demonstrated changes reflecting improved extracellular matrix and dermal integrity, lymphatic drainage, mitigation of inflammation, cellular clearance and recycling, and adipocyte metabolism. This study provides the rationale and preclinical support for the use of TTC as a standalone agent to improve body skin quality or in combination with body contouring procedures. J Drugs Dermatol. 2021;20(10):1041-1044. doi:10.36849/JDD.6401.
Databáze: OpenAIRE