Validity of the 6 minute walk test in facioscapulohumeral muscular dystrophy

Autor:	Katy, Eichinger, Chad, Heatwole, Susanne, Heininger, Nikia, Stinson, Carly, Matichak Stock, Carla, Grosmann, Kathryn R, Wagner, Rabi, Tawil, Jeffrey M, Statland
Rok vydání:	2016
Předmět:	Adult Aged 80 and over Male Adolescent Reproducibility of Results Walk Test Walking Middle Aged Severity of Illness Index Muscular Dystrophy Facioscapulohumeral Article Young Adult Cross-Sectional Studies Humans Female Muscle Strength Prospective Studies Aged Retrospective Studies
Zdroj:	Musclenerve. 55(3)
ISSN:	1097-4598
Popis:	In preparation for future clinical trials, we determined the reliability, relationship to measures of disease severity, and consistency across sites of the 6 Minute Walk Test (6MWT) in patients with facioscapulohumeral muscular dystrophy (FSHD).Genetically defined and clinically affected FSHD participants at 2 sites performed the 6MWT, the Timed Up and Go, and the 30 foot Go/Timed 10 meter test as measures of mobility using standard procedures.Eight-six participants representing the full range of severity performed the 6MWT. The mean 6MWT distance was 404.3 meters (SD 123.9), with no difference between sites. The 6MWT was reliable (n = 25; intraclass correlation coefficient = 0.99) and demonstrated moderate to strong correlations with lower extremity strength, functional outcomes, and FSHD Clinical Score.The 6MWT is reliable and is associated with other measures of FSHD disease severity. Future directions include assessing its sensitivity to disease progression. Muscle Nerve 55: 333-337, 2017.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4bccd84da0705a8f186a1c14fd588498 https://pubmed.ncbi.nlm.nih.gov/27421252 Zobrazit plný text záznamu Plný text