| Autor: |
S, Lipińska, M, Orłowska-Majdak, W Z, Traczyk |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 43(4) |
| ISSN: |
0867-5910 |
| Popis: |
In urethane-chloralose anaesthesia the pituitary gland was exposed by transpharyngeal approach in rats. The anterior lobe was removed and the posterior lobe was incubated in situ, that is in conditions of anatomical integrity of the hypothalamus with the posterior pituitary lobe. The 15-min samples of the medium incubating the posterior pituitary lobe in situ were collected. Vasopressin (AVP) content in the incubation medium was determined by radioimmunoassay. The stimulation of preganglionic fibers of the superior cervical ganglion (SCG) with alternate short (5 s) bursts of electric pulses with short (5 s) breaks did not change AVP release. However, stimulation of preganglionic fibres with alternate long (30 s) bursts of electric pulses with long (30 s) breaks evoked an increase in AVP release after some latency. Probably, at the hypothalamic or posterior pituitary level temporal summation should occur affecting vasopressinergic neurons or their endings and evoking AVP release. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
