Alkaline phosphatase activity in plasma of pregnant chagasic patients

Autor: M J, Sartori, S, Lin, R E, Fretes, L, Ruiz Moreno, L, Goldemberg, S P, de Fabro
Rok vydání: 1997
Předmět:
Zdroj: Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina). 55(1-2)
ISSN: 0014-6722
Popis: The kinetic properties of plasma placental alkaline phosphatase patients with Chagas' disease were studied. When Cl2Mg was used as activator the same increase of activity (17-20%) was found in the chagasic and non chagasic groups. The enzyme was not inhibited by F-ion in any of the groups. No significant differences were detected between the two groups (chagasic and non chagasic) when the enzyme was treated with inhibitors such as EDTA and L-phenylalanine. However, when the CN-ion was used, the enzyme of the normal pregnant women followed a Michaelian curve, whereas in the chagasic group a sigmoideal plot was observed. Thus, the Hill coefficient was 1.1 for the normal group and over 1.5 for the chagasic.
Databáze: OpenAIRE