| Autor: |
Yuya, Nogami, Kouji, Banno, Haruko, Irie, Miho, Iida, Yohei, Masugi, Koji, Murakami, Daisuke, Aoki |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Anticancer research. 35(4) |
| ISSN: |
1791-7530 |
| Popis: |
This study investigated whether dual-phase scanning (DPS) with 18-fludeoxyglucose positron emission tomography -computed tomography (FDG PET-CT) improves diagnosis of lymph node metastasis (LNM) in gynecologic malignancies, compared to mono-phase scanning (MPS).The study included 139 patients who underwent PET-CT followed by systemic lymph node dissection. PET-CT scans were obtained twice. The maximum standardized uptake value (SUVmax) was measured and the retention index (RI) was calculated as the % change from the early to the delayed scan. The optimal threshold of RI was determined using a receiver operating characteristic (ROC) curve. Diagnostic efficacies were calculated for MPS and DPS using pathological results.In total, 1,879 regions were dissected. The optimal RI was 9%. The sensitivity, specificity and accuracy were 35.8%, 99.0% and 96.8% for MPS and 26.9%, 99.6% and 97.0% for DPS, respectively. Specificity was significantly improved by DPS and accuracy was also improved, but not significantly.DPS had an unsatisfactory impact on the diagnostic efficacy for LNM. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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