[Mapping of the genetic locus determining the degree of natural resistance to erythromycin in Salmonella]

Autor:	N B, Gamaleia
Rok vydání:	1978
Předmět:	Salmonella typhimurium Cell Membrane Permeability Transduction Genetic Conjugation Genetic Mutation Chromosome Mapping Drug Resistance Microbial Chromosomes Bacterial Erythromycin
Zdroj:	Zhurnal mikrobiologii, epidemiologii i immunobiologii. (1)
ISSN:	0372-9311
Popis:	The locus which determines ordinary (natural--ery or) level of resistance to erythromycin in Salmonella has been mapped. According to the results of conjugation mating and the analysis of the properties' transfer gradient this region is localized next to his--locus, the gene order being; trp--his--eryor. However, no contransduction of eryor--locus with his--gene has been demonstrated. An assumption on a possible mechanism of alteration of natural level of erythromycin resistance in S. typhimurium mutants Er-4 and Es-1 (received earlier) has been made. This mechanism is connected with alterations in cell permeability.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4b89c5b75fcdcedbb200e7c6135bce5c https://pubmed.ncbi.nlm.nih.gov/343451 Zobrazit plný text záznamu