Reemergence of sucrose nephropathy: acute renal failure caused by high-dose intravenous immune globulin therapy

Autor:	R, Zhang, H M, Szerlip
Rok vydání:	2000
Předmět:	Male Sucrose Osmolar Concentration Sodium Age Factors Oliguria Immunoglobulins Intravenous Hemodiafiltration Recovery of Function Acute Kidney Injury Kidney Tubules Proximal Risk Factors Acute Disease Edema Humans Kidney Diseases Aged Demyelinating Diseases
Zdroj:	Southern medical journal. 93(9)
ISSN:	0038-4348
Popis:	Sucrose nephropathy was first described more than 50 years ago. The disorder is characterized by acute renal failure caused by the uptake of sucrose by renal proximal tubule cells with subsequent cellular swelling and occlusion of the tubule lumen. Approximately 114 cases of renal failure have been associated with high-dose intravenous immune globulin (IVIG) therapy. Almost all cases were caused by preparations containing large amounts of sucrose. Clinicians should consider using IVIG preparations containing no sucrose in patients who are at high risk for renal failure. Risk factors include older age, baseline renal failure, and volume contraction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4b6c298db9deef8f8ff81c7ea51da769 https://pubmed.ncbi.nlm.nih.gov/11005352 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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