| Autor: |
E R, Bevan, M J, Powell, M A, Toleman, C M, Thomas, L J V, Piddock, P M, Hawkey |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
The Journal of hospital infection. 114 |
| ISSN: |
1532-2939 |
| Popis: |
The global prevalence of extended-spectrum beta-lactamase-producing Escherichia coli is rising and is dominated by blaTo determine the conjugative ability of CTX-M-EC acquired by healthy volunteers after travel to South Asia, the proportion of travel-acquired CTX-M-EC where blaFaecal samples were collected pre- and post-travel from 23 volunteers who visited South Asia, and CTX-M-EC were cultured. After short- and long-read sequencing, 10 plasmid sequences were identified and compared with previously sequenced plasmids in GenBank. Conjugation to E. coli K-12 was undertaken using filter mating.Thirty-five percent of CTX-M-EC isolates tested transferred the blaGlobally successful epidemic plasmids are involved in the spread of CTX-M-EC. Targeted strategies may be used to displace such plasmids from the host strain as part of efforts in infection prevention and control in healthcare settings. Bacteria with bla |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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