| Autor: |
K P, Swathi, Saravanan, Jayaram, Deepa, Sugumar, Emdormi, Rymbai |
| Rok vydání: |
2020 |
| Zdroj: |
Chinese herbal medicines. 13(2) |
| ISSN: |
2589-3610 |
| Popis: |
The anti-inflammatory activity of the EECT was evaluated by carrageenan and histamine-induced paw edema.EECT showed a significant reduction in mean paw edema volume in both carrageenan and histamine-induced inflammation. The efficacy of EECT in rheumatoid arthritis was tested against Freund's complete adjuvant (CFA) induced arthritic model in Wistar rats. The anti-arthritic effect of EECT was determined by systematic scoring of arthritis symptoms and measuring paw edema. A considerable decrease in paw diameter was observed in the EECT (200 and 400 mg/kg) and diclofenac (10 mg/kg) treated groups after day 7. Diclofenac (10 mg/kg) and EECT (400 mg/kg) showed a significant reduction in paw diameter from day 14 compared with CFA control (This study provides a pharmacological rationale for the traditional use of |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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