[Mathematical modeling of energy coupling in mitochondria in frames of proton-chemical hypothesis]

Autor:	V V, Lemeshko, A G, Anishkin
Rok vydání:	1998
Předmět:	Electron Transport Animals Humans Models Theoretical Models Biological Oxidative Phosphorylation Mitochondria
Zdroj:	Biofizika. 43(2)
ISSN:	0006-3029
Popis:	The dependence of ATP-synthesis and mitochondria respiration rates on membrane potential was analyzed in frames of proton-chemical hypothesis of oxidative phosphorylation. The mathematical and electrical models of the unit of energy coupling are proposed. Computer analysis of the mathematical model allowed to obtain the theoretical dependence of the rates of ATP synthesis and of the respiration on the membrane potential. Both of all are in good qualitative agreement with experimental data, contradicting chemiosmotic hypothesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4b444560c36b3a5990f33941f7424eed https://pubmed.ncbi.nlm.nih.gov/9591105 Zobrazit plný text záznamu