| Autor: |
H R, van Buuren, A, Wils, E A J, Rauws, B, van Hoek, J P H, Drenth, E J, Kuipers, P M T, Pattynama |
| Jazyk: |
Dutch; Flemish |
| Rok vydání: |
2008 |
| Předmět: |
|
| Zdroj: |
Nederlands tijdschrift voor geneeskunde. 152(11) |
| ISSN: |
0028-2162 |
| Popis: |
The main options for secondary prevention of gastrooesophageal variceal bleeding are endoscopic therapy and treatment with propranolol. Creation ofa transjugular intrahepatic portosystemic shunt (TIPS) is currently considered a valuable secondary 'rescue' treatment when other therapies fail. Recent data suggest that the use of covered stents markedly increases the efficacy of TIPS, compared with conventional uncovered stents. Therefore, a multicentre randomised trial was designed to compare the effects of TIPS using covered stents with those of endoscopic therapy plus propranolol in patients with a first or second episode ofgastro-oesophageal variceal bleeding. TIPS will be performed in 4 university centres with relevant expertise. The trial will hopefully gain nationwide support, and all centres in The Netherlands are cordially invited to participate. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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