[Cultured epidermis in the treatment of leg ulcer: 'edge effect' and correlation with keratinocyte proliferation index]

Autor:	V, Giannotti, N, Pimpinelli, V, Mariotti, L, Borgognoni, U M, Reali
Rok vydání:	1990
Předmět:	Aged 80 and over Keratinocytes Time Factors Chronic Disease Leg Ulcer Humans Female Epidermis Middle Aged Cell Division Cells Cultured Aged Follow-Up Studies
Zdroj:	Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. 125(4)
ISSN:	0392-0488
Popis:	Cultured keratinocyte grafting (KG) of chronic leg ulcers produces an impressive stimulation of host epithelization by an effect on the edge of the ulcer, which starts to grow in rapidly ("edge effect"). In 5 patients with chronic leg ulcers treated by KG, we have studied the proliferation index of the epidermis of the edge and of the graft area and that of secondary culture keratinocytes. The aim of the study was to correlate this parameter with the clinical evolution of the treated lesions. We found a significant correlation between the proliferation index of the edge epidermis and the clinical evidence of "edge effect".
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4aba7f5117223deaf18e6e67300b7145 https://pubmed.ncbi.nlm.nih.gov/2228043 Zobrazit plný text záznamu