A life-threatening flecainide overdose treated with intravenous fat emulsion

Autor: Heather, Ellsworth, Samuel J, Stellpflug, Jon B, Cole, Joseph A, Dolan, Carson R, Harris
Rok vydání: 2011
Předmět:
Zdroj: Pacing and clinical electrophysiology : PACE. 36(3)
ISSN: 1540-8159
Popis: Flecainide is a Vaughan Williams Class Ic antidysrhythmic associated with PR, QRS, and QTc prolongation on the electrocardiogram and development of life-threatening cardiac toxicity in overdose. The cornerstone of treatment is fluid resuscitation and the administration of magnesium and sodium bicarbonate. We report a case of flecainide overdose associated with life-threatening hemodynamic compromise successfully treated with intravenous fat emulsion (IFE) therapy. IFE should be considered as a novel adjunctive therapy in patients with life-threatening toxicity following flecainide overdose.
Databáze: OpenAIRE