Clr-f expression regulates kidney immune and metabolic homeostasis

Autor:	Haggag S, Zein, Elias, Abou-Samra, Michal, Scur, Alex, Gutsol, Clayton W, Hall, Bishal, Dasgupta, Lara, Gharibeh, Turki, Abujamel, Daniel, Medina-Luna, Gayani S, Gamage, Tessa J, Pelino, Mona, Nemer, Mir Munir A, Rahim, Alexander, Steinle, Brendon D, Parsons, Andrew P, Makrigiannis
Rok vydání:	2021
Předmět:	Killer Cells Natural Mice Inbred C57BL Mice Animals Homeostasis Lectins C-Type Kidney Lipids NK Cell Lectin-Like Receptor Subfamily B
Zdroj:	Scientific reports. 12(1)
ISSN:	2045-2322
Popis:	The C-type lectin-related protein, Clr-f, encoded by Clec2h in the mouse NK gene complex (NKC), is a member of a family of immune regulatory lectins that guide immune responses at distinct tissues of the body. Clr-f is highly expressed in the kidney; however, its activity in this organ is unknown. To assess the requirement for Clr-f in kidney health and function, we generated a Clr-f-deficient mouse (Clr-f
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4a1ea3c2ee46e93ef4561df5f637dea9 https://pubmed.ncbi.nlm.nih.gov/35318366 Full text from SpringerLink