| Autor: |
A I, Nikolaev, A V, Martynenko, B B, Kalmyrzaev, L I, Inozemtseva, V I, Dubovaia, G, Hunsmann, V, Bodemer, V Z, Tarandul |
| Rok vydání: |
2001 |
| Předmět: |
|
| Zdroj: |
Molekuliarnaia biologiia. 35(1) |
| ISSN: |
0026-8984 |
| Popis: |
Mitochondrial genes that are overexpressed in human and monkey B-cell non-Hodgkin lymphomas (B-NHLs) were sought via subtraction hybridization, cloning, and differential screening of the resulting cDNA libraries. The cDNAs of mitochondrial genes made an appreciable proportion of all lymphoma-specific cDNAs. Lymphomogenesis was associated with overexpression of a mitochondrial gene set which varied with lymphoma type and always included NADHIV. A possible association between overexpression of certain mitochondrial genes and cell malignant transformation is discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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