Popis: |
To characterize structural-functional state of the heart by means of uni-, two-dimentional and doppler echocardiography in impulse regimen; to evaluate lipid metabolism in patients with scleroderma systematica (SS) and systemic lupus erythematosus (SLE).The examination of 35 SS and 38 SLE patients included clinical examination, echocardioscopy with doppler cardiography, measurements of serum concentrations of total cholesterol, triglycerides, low and high density lipoproteins, atherogenic index.In SS patients central hemodynamics reflects hyperdynamics. In intact contractility, diastolic function of the ventricles is impaired. Elevated atherogenicity of the serum was found in both the groups.According to echocardiography SLE and SS are associated with changes in both intracardiac and central hemodynamics. High atherogenicity of the serum may appear an additional factor of risk of hemodynamic disturbances. |