| Autor: |
Michelle S, Liberato, Nayara G S, Cavalcante, P Abinaya, Sindu, Mônica J, Rodrigues-Jesus, Pavel, Zelenovskii, Ana C O, Carreira, Maurício S, Baptista, Mari C, Sogayar, Luís C S, Ferreira, Luiz H, Catalani |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Soft matter. 17(48) |
| ISSN: |
1744-6848 |
| Popis: |
The formation of hydrogels by photosensitized oxidation and crosslinking of histidine-derived polymers is demonstrated for the first time. The photooxidation of pendant His mediated by singlet oxygen was used to promote covalent coupling by its dimerization. As a proof-of-concept, two systems were studied: (i) chondroitin sulfate (CS) functionalized with His, and (ii) an elastin-like peptide (ELP) containing His produced by recombinant techniques. Both materials were crosslinked by irradiation at 425 nm in the presence of Zn-porphyrin derivatives yielding His-based hydrogels. The molecular structure and physicochemical properties of ELP-His and other 5 ELPs with photooxidizable amino acids were studied |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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